Cashew nut is widely consumed all over the world. It is a tropical plant belonging to the genus Anacardium. At the end we will discuss Cashew Allergy Treatments and People allergic to Cashews, How Can you outgrow a cashew allergy? Cashewis a nut, part of an evergreen tree. Sesame allergy: a growing food allergy of global proportions? Ann Allergy Asthma Immunol 2005 95(1):1-11.This post is all about Cashew Allergy Symptoms, Cashew Allergy in Adults, Babies and Toddlers. Cashew allergy: observations of 42 children without associated peanut allergy. Rance F, Bidat E, Bourrier T, Sabouraud D. Allergenicity of gourmet nut oils processed by different methods. Vicilin allergens of peanut and tree nuts (walnut, hazelnut and cashew Teuber SS, Brown RL, Haapanen LA. Barre A, Sordet C, Culerrier R, Rancé F, Didier A, Rougé P. Ana o 1, a cashew (Anacardium occidental) allergen of the vicilin seed storage protein family. Wang F, Robotham JM, Teuber SS, Tawde P, Sathe SK, Roux KH. Allergy to Anacardiaceae: description of cashew and pistachio nut allergens. Garcia F, Moneo I, Fernandez B, Garcia-Menaya JM, Blanco J, Juste S, Gonzalo. Characterization of the soluble allergenic proteins of cashew nut (Anacardium occidentale L). Teuber SS, Sathe SK, Peterson WR, Roux KH. World Allergy Organization Journal 2012 5:S152.ġ. A rare case of food-induced anaphylaxis to pink peppercorns. Thank you again for your inquiry and we hope this response is helpful to you.ġ. None the less,from the above you also see it is difficult to draw any definitive clinical conclusions from these cross-reactive patterns except to say that there is probably an increased risk of clinical crossreactivity between all of the above mentioned foods with the strongest being for pistachio and cashew themselves. Andin direct answer to your inquiry there is potential crossreactivity between both of these and any member of the Anacardiaceae family as evidenced by the single case of a patient exhibiting clinical reactions to peppercorn as well as cashew and pistachio. As with pistachio, pectin exhibits crossreactivity with cashew.įrom the above, you can see that there is a very complex in vitro, immunologic crossreactivity pattern existing between cashew and pistachio and between these two foods and other allergens. Some immunologic reactivity has also been noted for sesamum indicum and buckwheat. Evidence for cross-reactivity between cashew and other foods exists for hazelnut, walnut, and perhaps peanut. Similar but separate cross-reactive patterns have been seen for cashew. Other cross-reactivities for pistachio based on case reports might be pectin and other foods containing the lipid transfer protein. Additional foods cross-react with pistachio including mango and artemisia. Numerous studies have of course demonstrated crossreactivity to cashew and pistachio. Pistachio has a very close relationship, as noted, with the Anacardiaceae family. There is also a possibility that a lipid transfer protein is an active antigen in pistachio. Very similar allergens are found in pistachio including an albumin, globulin, vicilin-like protein, and pistachio also contains a magnesium superoxide dismutase. At least four distinct allergens have been noted in cashew including a vicilin-like protein, a profilin, an albumin, and a globulin. Of this family, probably the most extensive work regarding crossreactivity exists for cashew and pistachio. Pistachio has been classified as part of this family as well, but some authorities place it in a family of its own (Pistaciaceae). Notably it contains mango, poison sumac, poison ivy, yellow mombin, the smoke tree, marula, and cuachalalate. This family includes a number of different plants besides cashew and peppercorn. But, as you note, it would not be unexpected for members of the same botanical family to crossreact even though this is not universally the case. It is of course reasonable to assume that a cross-reacting antigen may have been responsible since the patient was also allergic to cashews and pistachios, but unless immunologic studies are performed, one could not establish this definitively. This group of plants has also been called the sumac family. It is only implied because the pink peppercorns are in the same family as cashews. No immunologic in vitro studies were performed to demonstrate actual crossreactivity. The reaction the patient experienced does not actually establish crossreactivity between pink peppercorns and other members of the family Anacardiaceae. I believe perhaps there may be some confusion regarding the case report that you cited (1).
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